SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling

Macropinocytosis is essential for myeloid cells to survey their environment and for growth of RAS-transformed cancer cells. Several growth factors and inflammatory stimuli are known to induce macropinocytosis, but its endogenous inhibitors have remained elusive. Stimulation of Roundabout receptors b...

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Detalles Bibliográficos
Autores principales: Bhosle, Vikrant K., Mukherjee, Tapas, Huang, Yi-Wei, Patel, Sajedabanu, Pang, Bo Wen (Frank), Liu, Guang-Ying, Glogauer, Michael, Wu, Jane Y., Philpott, Dana J., Grinstein, Sergio, Robinson, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431850/
https://www.ncbi.nlm.nih.gov/pubmed/32807784
http://dx.doi.org/10.1038/s41467-020-17651-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431850/
https://www.ncbi.nlm.nih.gov/pubmed/32807784
http://dx.doi.org/10.1038/s41467-020-17651-1

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