Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction

Epigenetic information is transmitted from mother to daughter cells through mitosis. Here, to identify factors that might play a role in conveying epigenetic memory through cell division, we report on the isolation of unfixed, native chromosomes from metaphase-arrested cells using flow cytometry and...

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Detalles Bibliográficos
Autores principales: Djeghloul, Dounia, Patel, Bhavik, Kramer, Holger, Dimond, Andrew, Whilding, Chad, Brown, Karen, Kohler, Anne-Céline, Feytout, Amelie, Veland, Nicolas, Elliott, James, Bharat, Tanmay A. M., Tarafder, Abul K., Löwe, Jan, Ng, Bee L., Guo, Ya, Guy, Jacky, Huseyin, Miles K., Klose, Robert J., Merkenschlager, Matthias, Fisher, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431861/
https://www.ncbi.nlm.nih.gov/pubmed/32807789
http://dx.doi.org/10.1038/s41467-020-17823-z

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