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Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease

Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes, regulates various microbial metabolic pathways. However, no studies have examined protein Kac at the microbiome level, and it remains unknown whether Kac level is altered in patient microbiomes. Herein, we us...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Ning, Zhibin, Mayne, Janice, Yang, Yidai, Deeke, Shelley A., Walker, Krystal, Farnsworth, Charles L., Stokes, Matthew P., Couture, Jean-François, Mack, David, Stintzi, Alain, Figeys, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431864/
https://www.ncbi.nlm.nih.gov/pubmed/32807798
http://dx.doi.org/10.1038/s41467-020-17916-9