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A history of the roles of cytochrome P450 enzymes in the toxicity of drugs

The history of drug metabolism began in the 19th Century and developed slowly. In the mid-20th Century the relationship between drug metabolism and toxicity became appreciated, and the roles of cytochrome P450 (P450) enzymes began to be defined in the 1960s. Today we understand much about the metabo...

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Detalles Bibliográficos
Autor principal: Guengerich, F. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431904/
https://www.ncbi.nlm.nih.gov/pubmed/32837681
http://dx.doi.org/10.1007/s43188-020-00056-z