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Serum Free Immunoglobulins Light Chains: A Common Feature of Common Variable Immunodeficiency?
Serum free light chain (sFLC) is a recently proposed biomarker for CVID diagnosis. Most CVID patients present low or undetectable sFLC up to 10-fold lower compared to other primary antibody deficiencies. Given that κ and λ light chains are normally secreted in excess with respect to immunoglobulins,...
Autores principales: | Guevara-Hoyer, Kissy, Ochoa-Grullón, Juliana, Fernández-Arquero, Miguel, Cárdenas, Mariacruz, Pérez de Diego, Rebeca, Sánchez-Ramón, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431983/ https://www.ncbi.nlm.nih.gov/pubmed/32849664 http://dx.doi.org/10.3389/fimmu.2020.02004 |
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