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Cell Sheets from Adipose Tissue MSC Induce Healing of Pressure Ulcer and Prevent Fibrosis via Trigger Effects on Granulation Tissue Growth and Vascularization

We report a comparative study of multipotent mesenchymal stromal cells (MSC) delivered by injection, MSC-based cell sheets (CS) or MSC secretome to induce healing of cutaneous pressure ulcer in C57Bl/6 mice. We found that transplantation of CS from adipose-derived MSC resulted in reduction of fibros...

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Detalles Bibliográficos
Autores principales: Alexandrushkina, Natalya, Nimiritsky, Peter, Eremichev, Roman, Popov, Vladimir, Arbatskiy, Mikhail, Danilova, Natalia, Malkov, Pavel, Akopyan, Zhanna, Tkachuk, Vsevolod, Makarevich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432086/
https://www.ncbi.nlm.nih.gov/pubmed/32759725
http://dx.doi.org/10.3390/ijms21155567