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Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells

A decline in immune function with aging has been reported. Regulatory T cell (Treg) induction is known to decrease with age, and elucidating the underlying mechanism is important for preventing age-related diseases due to age-related chronic inflammation. In the intestine, dendritic cells (DCs) play...

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Detalles Bibliográficos
Autores principales: Takano, Tomohiro, Kotaki, Ryutaro, Park, Jihyun, Yoshida, Tadashi, Wakatsuki, Yoshio, Tanokura, Masaru, Miyakawa, Takuya, Takahashi, Kyoko, Nakajima-Adachi, Haruyo, Hachimura, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432217/
https://www.ncbi.nlm.nih.gov/pubmed/32849526
http://dx.doi.org/10.3389/fimmu.2020.01555