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Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells
A decline in immune function with aging has been reported. Regulatory T cell (Treg) induction is known to decrease with age, and elucidating the underlying mechanism is important for preventing age-related diseases due to age-related chronic inflammation. In the intestine, dendritic cells (DCs) play...
Autores principales: | Takano, Tomohiro, Kotaki, Ryutaro, Park, Jihyun, Yoshida, Tadashi, Wakatsuki, Yoshio, Tanokura, Masaru, Miyakawa, Takuya, Takahashi, Kyoko, Nakajima-Adachi, Haruyo, Hachimura, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432217/ https://www.ncbi.nlm.nih.gov/pubmed/32849526 http://dx.doi.org/10.3389/fimmu.2020.01555 |
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