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Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes

The BVA/KC (British Veterinary Association/Kennel Club) and FCI (Fédération Cynologique Internationale) are the main screening schemes used to evaluate the status of canine hip dysplasia (HD) in Europe. Jointly utilizing HD records from both BVA/KC and FCI schemes could improve the reliability of ge...

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Autores principales: Wang, Shizhi, Friedrich, Juliane, Strandberg, Erling, Arvelius, Per, Wiener, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432227/
https://www.ncbi.nlm.nih.gov/pubmed/32850996
http://dx.doi.org/10.3389/fvets.2020.00386
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author Wang, Shizhi
Friedrich, Juliane
Strandberg, Erling
Arvelius, Per
Wiener, Pamela
author_facet Wang, Shizhi
Friedrich, Juliane
Strandberg, Erling
Arvelius, Per
Wiener, Pamela
author_sort Wang, Shizhi
collection PubMed
description The BVA/KC (British Veterinary Association/Kennel Club) and FCI (Fédération Cynologique Internationale) are the main screening schemes used to evaluate the status of canine hip dysplasia (HD) in Europe. Jointly utilizing HD records from both BVA/KC and FCI schemes could improve the reliability of genetic evaluation within and across countries. In this study, HD scores for German shepherd dogs (GSDs) in the UK (using the BVA/KC scheme) and Sweden (using the FCI scheme) were used to investigate how to better operate joint genetic evaluations across the two schemes. It was shown that under a bivariate model, which regarded BVA/KC and FCI scores as different traits, the estimated genetic correlations between the UK and Swedish GSD populations were the same when using BVA/KC total or worse hip scores and for single-country or joint analysis of both the UK and Swedish populations. Under a univariate model that converted BVA/KC scores into FCI scores, the predictability of estimated breeding values was slightly improved by performing a joint analysis.
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spelling pubmed-74322272020-08-25 Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes Wang, Shizhi Friedrich, Juliane Strandberg, Erling Arvelius, Per Wiener, Pamela Front Vet Sci Veterinary Science The BVA/KC (British Veterinary Association/Kennel Club) and FCI (Fédération Cynologique Internationale) are the main screening schemes used to evaluate the status of canine hip dysplasia (HD) in Europe. Jointly utilizing HD records from both BVA/KC and FCI schemes could improve the reliability of genetic evaluation within and across countries. In this study, HD scores for German shepherd dogs (GSDs) in the UK (using the BVA/KC scheme) and Sweden (using the FCI scheme) were used to investigate how to better operate joint genetic evaluations across the two schemes. It was shown that under a bivariate model, which regarded BVA/KC and FCI scores as different traits, the estimated genetic correlations between the UK and Swedish GSD populations were the same when using BVA/KC total or worse hip scores and for single-country or joint analysis of both the UK and Swedish populations. Under a univariate model that converted BVA/KC scores into FCI scores, the predictability of estimated breeding values was slightly improved by performing a joint analysis. Frontiers Media S.A. 2020-08-11 /pmc/articles/PMC7432227/ /pubmed/32850996 http://dx.doi.org/10.3389/fvets.2020.00386 Text en Copyright © 2020 Wang, Friedrich, Strandberg, Arvelius and Wiener. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Wang, Shizhi
Friedrich, Juliane
Strandberg, Erling
Arvelius, Per
Wiener, Pamela
Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes
title Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes
title_full Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes
title_fullStr Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes
title_full_unstemmed Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes
title_short Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes
title_sort methods to improve joint genetic evaluation of canine hip dysplasia across bva/kc and fci screening schemes
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432227/
https://www.ncbi.nlm.nih.gov/pubmed/32850996
http://dx.doi.org/10.3389/fvets.2020.00386
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