Cargando…

Exploiting the Complexities of Glioblastoma Stem Cells: Insights for Cancer Initiation and Therapeutic Targeting

The discovery of glioblastoma stem cells (GSCs) in the 2000s revolutionized the cancer research field, raising new questions regarding the putative cell(s) of origin of this tumor type, and partly explaining the highly heterogeneous nature of glioblastoma (GBM). Increasing evidence has suggested tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vieira de Castro, Joana, Gonçalves, Céline S., Hormigo, Adília, Costa, Bruno M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432229/ https://www.ncbi.nlm.nih.gov/pubmed/32722427 http://dx.doi.org/10.3390/ijms21155278

Ejemplares similares

Unveiling YKL-40, from Serum Marker to Target Therapy in Glioblastoma
por: Iwamoto, Fabio M., et al.
Publicado: (2014)

The CNS and the Brain Tumor Microenvironment: Implications for Glioblastoma Immunotherapy
por: Desland, Fiona A., et al.
Publicado: (2020)

MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma
por: Miranda-Gonçalves, Vera, et al.
Publicado: (2021)

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma
por: Mitchell, Kelly, et al.
Publicado: (2023)

361 WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma
por: Hubert, Christopher, et al.
Publicado: (2023)

Intracellular Autofluorescence as a New Biomarker for Cancer Stem Cells in Glioblastoma
por: Vieira de Castro, Joana, et al.
Publicado: (2021)

Impact of mesenchymal stem cells’ secretome on glioblastoma pathophysiology
por: Vieira de Castro, Joana, et al.
Publicado: (2017)

Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report
por: Umphlett, Melissa, et al.
Publicado: (2020)

Tumoral and immune heterogeneity in an anti-PD-1-responsive glioblastoma: a case study
por: Restrepo, Paula, et al.
Publicado: (2020)

Chronic Stress Does Not Influence the Survival of Mouse Models of Glioblastoma
por: Lopes, Marta, et al.
Publicado: (2022)

Glioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma
por: Kalkan, Rasime
Publicado: (2015)

Therapeutic Targeting of Cancer Stem Cells: Integrating and Exploiting the Acidic Niche
por: Vander Linden, Catherine, et al.
Publicado: (2019)

Glioblastoma Microenvironment and Invasiveness: New Insights and Therapeutic Targets
por: Erices, José Ignacio, et al.
Publicado: (2023)

Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets
por: Jhanwar-Uniyal, Meena, et al.
Publicado: (2015)

Insights into Nuclear G-Protein-Coupled Receptors as Therapeutic Targets in Non-Communicable Diseases
por: Gonçalves-Monteiro, Salomé, et al.
Publicado: (2021)

Targeting JNK for therapeutic depletion of stem-like glioblastoma cells
por: Matsuda, Ken-ichiro, et al.
Publicado: (2012)

Glioblastoma Metabolism: Insights and Therapeutic Strategies
por: Bernhard, Chloé, et al.
Publicado: (2023)

Planning TTFields treatment using the NovoTAL system-clinical case series beyond the use of MRI contrast enhancement
por: Connelly, Jennifer, et al.
Publicado: (2016)

A New Chalcone Derivative with Promising Antiproliferative and Anti-Invasion Activities in Glioblastoma Cells
por: Mendanha, Daniel, et al.
Publicado: (2021)

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide
por: Pojo, Marta, et al.
Publicado: (2015)

WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma
por: Gonçalves, Céline S., et al.
Publicado: (2018)

Exploiting the Stemness and Chemoresistance Transcriptome of Ewing Sarcoma to Identify Candidate Therapeutic Targets and Drug-Repurposing Candidates
por: Roundhill, Elizabeth Ann, et al.
Publicado: (2023)

Crosstalk between glial and glioblastoma cells triggers the “go-or-grow” phenotype of tumor cells
por: Oliveira, Ana Isabel, et al.
Publicado: (2017)

Exploiting Radiation Therapy to Restore Immune Reactivity of Glioblastoma
por: De Martino, Mara, et al.
Publicado: (2021)

Exploiting radiation immunostimulatory effects to improve glioblastoma outcome
por: Awada, Hala, et al.
Publicado: (2022)

Glioblastoma stem cells and Wnt signaling pathway: molecular mechanisms and therapeutic targets
por: Guan, Ruoyu, et al.
Publicado: (2020)

Targeting Glioblastoma Stem Cells to Overcome Chemoresistance: An Overview of Current Therapeutic Strategies
por: Kang, Hyunkoo, et al.
Publicado: (2022)

Editorial: Systemic immune dysregulation in malignant disease: Insights, monitoring and therapeutic exploitation
por: Christopoulos, Petros, et al.
Publicado: (2023)

Exploiting LRRC15 as a Novel Therapeutic Target in Cancer
por: Ray, Upasana, et al.
Publicado: (2022)

Extracellular RNAs in Bacterial Infections: From Emerging Key Players on Host-Pathogen Interactions to Exploitable Biomarkers and Therapeutic Targets
por: Pita, Tiago, et al.
Publicado: (2020)

Eph receptors as therapeutic targets in glioblastoma
por: Day, B W, et al.
Publicado: (2014)

HOTAIR is a therapeutic target in glioblastoma
por: Zhou, Xuan, et al.
Publicado: (2015)

Robot technology identifies a Parkinsonian therapeutics repurpose to target stem cells of glioblastoma
por: Vargas-Toscano, Andres, et al.
Publicado: (2020)

Therapeutic Targeting of Cancer Stem Cells in Human Glioblastoma by Manipulating the Renin-Angiotensin System
por: Tan, David C. H., et al.
Publicado: (2019)

Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma
por: Höbel, Sabrina, et al.
Publicado: (2011)

Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma
por: Yoshimoto, Koji, et al.
Publicado: (2012)

Crizotinib targets in glioblastoma stem cells
por: Junca, Audelaure, et al.
Publicado: (2017)

Exploitation of the Mediator complex by viruses
por: Rovnak, Joel, et al.
Publicado: (2022)

A mathematical model for targeting chemicals to tissues by exploiting complex degradation
por: Gardiner, Bruce S, et al.
Publicado: (2011)

Cadherin‐3 is a novel oncogenic biomarker with prognostic value in glioblastoma
por: Martins, Eduarda P., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5ev94ahv97v51o9dafif8von7e