Irradiation-Induced Upregulation of miR-711 Inhibits DNA Repair and Promotes Neurodegeneration Pathways

Radiotherapy for brain tumors induces neuronal DNA damage and may lead to neurodegeneration and cognitive deficits. We investigated the mechanisms of radiation-induced neuronal cell death and the role of miR-711 in the regulation of these pathways. We used in vitro and in vivo models of radiation-in...

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Detalles Bibliográficos
Autores principales: Sabirzhanov, Boris, Makarevich, Oleg, Barrett, James P., Jackson, Isabel L., Glaser, Ethan P., Faden, Alan I., Stoica, Bogdan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432239/
https://www.ncbi.nlm.nih.gov/pubmed/32718090
http://dx.doi.org/10.3390/ijms21155239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432239/
https://www.ncbi.nlm.nih.gov/pubmed/32718090
http://dx.doi.org/10.3390/ijms21155239

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