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Irradiation-Induced Upregulation of miR-711 Inhibits DNA Repair and Promotes Neurodegeneration Pathways
Radiotherapy for brain tumors induces neuronal DNA damage and may lead to neurodegeneration and cognitive deficits. We investigated the mechanisms of radiation-induced neuronal cell death and the role of miR-711 in the regulation of these pathways. We used in vitro and in vivo models of radiation-in...
Autores principales: | Sabirzhanov, Boris, Makarevich, Oleg, Barrett, James P., Jackson, Isabel L., Glaser, Ethan P., Faden, Alan I., Stoica, Bogdan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432239/ https://www.ncbi.nlm.nih.gov/pubmed/32718090 http://dx.doi.org/10.3390/ijms21155239 |
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