Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice

Background and Purpose: Diabetes mellitus increases stroke incidence and mortality and hampers functional recovery after stroke. Fingolimod has been shown to improve neurofunctional recovery and reduce brain infarction after ischemic injury in mice without comorbidities. In this work, we investigate...

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Detalles Bibliográficos
Autores principales: Li, Wanlu, He, Tingting, Jiang, Lu, Shi, Rubing, Song, Yaying, Mamtilahun, Muyassar, Ma, Yuanyuan, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Wang, Yongting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432267/
https://www.ncbi.nlm.nih.gov/pubmed/32848587
http://dx.doi.org/10.3389/fnins.2020.00842

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