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Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice

The genetic evolution of HIV-1 from its progenitor virus SIV following cross-species transmission is not well understood. Here we simulated the SIVcpz initial transmission to humans using humanized mice and followed the viral evolution during serial passages lasting more than a year. All three SIVcp...

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Detalles Bibliográficos
Autores principales:	Schmitt, Kimberly, Curlin, James, Remling-Mulder, Leila, Moriarty, Ryan, Goff, Kelly, O’Connor, Shelby, Stenglein, Mark, Marx, Preston, Akkina, Ramesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432304/ https://www.ncbi.nlm.nih.gov/pubmed/32849468 http://dx.doi.org/10.3389/fmicb.2020.01889

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