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Right Ventricular Diastolic Dysfunction after Marathon Run

It has been raised that marathon running may significantly impair cardiac performance. However, the post-race diastolic function has not been extensively analyzed. We aimed to assess whether the marathon run causes impairment of the cardiac diastole, which ventricle is mostly affected and whether th...

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Autores principales: Lewicka-Potocka, Zuzanna, Dąbrowska-Kugacka, Alicja, Lewicka, Ewa, Gałąska, Rafał, Daniłowicz-Szymanowicz, Ludmiła, Faran, Anna, Nabiałek-Trojanowska, Izabela, Kubik, Marcin, Kaleta-Duss, Anna Maria, Raczak, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432325/
https://www.ncbi.nlm.nih.gov/pubmed/32722206
http://dx.doi.org/10.3390/ijerph17155336
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author Lewicka-Potocka, Zuzanna
Dąbrowska-Kugacka, Alicja
Lewicka, Ewa
Gałąska, Rafał
Daniłowicz-Szymanowicz, Ludmiła
Faran, Anna
Nabiałek-Trojanowska, Izabela
Kubik, Marcin
Kaleta-Duss, Anna Maria
Raczak, Grzegorz
author_facet Lewicka-Potocka, Zuzanna
Dąbrowska-Kugacka, Alicja
Lewicka, Ewa
Gałąska, Rafał
Daniłowicz-Szymanowicz, Ludmiła
Faran, Anna
Nabiałek-Trojanowska, Izabela
Kubik, Marcin
Kaleta-Duss, Anna Maria
Raczak, Grzegorz
author_sort Lewicka-Potocka, Zuzanna
collection PubMed
description It has been raised that marathon running may significantly impair cardiac performance. However, the post-race diastolic function has not been extensively analyzed. We aimed to assess whether the marathon run causes impairment of the cardiac diastole, which ventricle is mostly affected and whether the septal (IVS) function is altered. The study included 34 male amateur runners, in whom echocardiography was performed two weeks before, at the finish line and two weeks after the marathon. Biventricular diastolic function was assessed not only with conventional Doppler indices but also using the heart rate-adjusted isovolumetric relaxation time (IVRTc). After the run, IVRTc elongated dramatically at the right ventricular (RV) free wall, to a lesser extent at the IVS and remained unchanged at the left ventricular lateral wall. The post-run IVRTc_IVS correlated with IVRTc_RV (r = 0.38, p < 0.05), and IVRTc_RV was longer in subjects with IVS hypertrophy (88 vs. 51 ms; p < 0.05). Participants with measurable IVRT_RV at baseline (38% of runners) had longer post-race IVRTc_IVS (102 vs. 83 ms; p < 0.05). Marathon running influenced predominantly the RV diastolic function, and subjects with measurable IVRT_RV at baseline or those with IVS hypertrophy can experience greater post-race diastolic fatigue.
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spelling pubmed-74323252020-08-24 Right Ventricular Diastolic Dysfunction after Marathon Run Lewicka-Potocka, Zuzanna Dąbrowska-Kugacka, Alicja Lewicka, Ewa Gałąska, Rafał Daniłowicz-Szymanowicz, Ludmiła Faran, Anna Nabiałek-Trojanowska, Izabela Kubik, Marcin Kaleta-Duss, Anna Maria Raczak, Grzegorz Int J Environ Res Public Health Article It has been raised that marathon running may significantly impair cardiac performance. However, the post-race diastolic function has not been extensively analyzed. We aimed to assess whether the marathon run causes impairment of the cardiac diastole, which ventricle is mostly affected and whether the septal (IVS) function is altered. The study included 34 male amateur runners, in whom echocardiography was performed two weeks before, at the finish line and two weeks after the marathon. Biventricular diastolic function was assessed not only with conventional Doppler indices but also using the heart rate-adjusted isovolumetric relaxation time (IVRTc). After the run, IVRTc elongated dramatically at the right ventricular (RV) free wall, to a lesser extent at the IVS and remained unchanged at the left ventricular lateral wall. The post-run IVRTc_IVS correlated with IVRTc_RV (r = 0.38, p < 0.05), and IVRTc_RV was longer in subjects with IVS hypertrophy (88 vs. 51 ms; p < 0.05). Participants with measurable IVRT_RV at baseline (38% of runners) had longer post-race IVRTc_IVS (102 vs. 83 ms; p < 0.05). Marathon running influenced predominantly the RV diastolic function, and subjects with measurable IVRT_RV at baseline or those with IVS hypertrophy can experience greater post-race diastolic fatigue. MDPI 2020-07-24 2020-08 /pmc/articles/PMC7432325/ /pubmed/32722206 http://dx.doi.org/10.3390/ijerph17155336 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lewicka-Potocka, Zuzanna
Dąbrowska-Kugacka, Alicja
Lewicka, Ewa
Gałąska, Rafał
Daniłowicz-Szymanowicz, Ludmiła
Faran, Anna
Nabiałek-Trojanowska, Izabela
Kubik, Marcin
Kaleta-Duss, Anna Maria
Raczak, Grzegorz
Right Ventricular Diastolic Dysfunction after Marathon Run
title Right Ventricular Diastolic Dysfunction after Marathon Run
title_full Right Ventricular Diastolic Dysfunction after Marathon Run
title_fullStr Right Ventricular Diastolic Dysfunction after Marathon Run
title_full_unstemmed Right Ventricular Diastolic Dysfunction after Marathon Run
title_short Right Ventricular Diastolic Dysfunction after Marathon Run
title_sort right ventricular diastolic dysfunction after marathon run
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432325/
https://www.ncbi.nlm.nih.gov/pubmed/32722206
http://dx.doi.org/10.3390/ijerph17155336
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