Beneficial Effects of Mineralocorticoid Receptor Antagonism on Myocardial Fibrosis in an Experimental Model of the Myxomatous Degeneration of the Mitral Valve

Mitral valve prolapse (MVP) patients develop myocardial fibrosis that is not solely explained by volume overload, but the pathophysiology has not been defined. Mineralocorticoid receptor antagonists (MRAs) improve cardiac function by decreasing cardiac fibrosis in other heart diseases. We examined t...

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Detalles Bibliográficos
Autores principales: Ibarrola, Jaime, Garaikoetxea, Mattie, Garcia-Peña, Amaia, Matilla, Lara, Jover, Eva, Bonnard, Benjamin, Cuesta, Maria, Fernández-Celis, Amaya, Jaisser, Frederic, López-Andrés, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432373/
https://www.ncbi.nlm.nih.gov/pubmed/32731636
http://dx.doi.org/10.3390/ijms21155372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432373/
https://www.ncbi.nlm.nih.gov/pubmed/32731636
http://dx.doi.org/10.3390/ijms21155372

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