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Beneficial Effects of Mineralocorticoid Receptor Antagonism on Myocardial Fibrosis in an Experimental Model of the Myxomatous Degeneration of the Mitral Valve
Mitral valve prolapse (MVP) patients develop myocardial fibrosis that is not solely explained by volume overload, but the pathophysiology has not been defined. Mineralocorticoid receptor antagonists (MRAs) improve cardiac function by decreasing cardiac fibrosis in other heart diseases. We examined t...
Autores principales: | Ibarrola, Jaime, Garaikoetxea, Mattie, Garcia-Peña, Amaia, Matilla, Lara, Jover, Eva, Bonnard, Benjamin, Cuesta, Maria, Fernández-Celis, Amaya, Jaisser, Frederic, López-Andrés, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432373/ https://www.ncbi.nlm.nih.gov/pubmed/32731636 http://dx.doi.org/10.3390/ijms21155372 |
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