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RORγ Structural Plasticity and Druggability

Retinoic acid receptor-related orphan receptor γ (RORγ) is a transcription factor regulating the expression of the pro-inflammatory cytokine IL-17 in human T helper 17 (Th17) cells. Activating RORγ can induce multiple IL-17-mediated autoimmune diseases but may also be useful for anticancer therapy....

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Detalles Bibliográficos
Autores principales:	Huang, Mian, Bolin, Shelby, Miller, Hannah, Ng, Ho Leung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432406/ https://www.ncbi.nlm.nih.gov/pubmed/32727079 http://dx.doi.org/10.3390/ijms21155329

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