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A Synthetic Epoxydocosapentaenoic Acid Analogue Ameliorates Cardiac Ischemia/Reperfusion Injury: The Involvement of the Sirtuin 3–NLRP3 Pathway
While survival rates have markedly improved following cardiac ischemia-reperfusion (IR) injury, the resulting heart damage remains an important issue. Preserving mitochondrial quality and limiting NLRP3 inflammasome activation is an approach to limit IR injury, in which the mitochondrial deacetylase...
Autores principales: | Darwesh, Ahmed M., Bassiouni, Wesam, Adebesin, Adeniyi Michael, Mohammad, Abdul Sattar, Falck, John R., Seubert, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432620/ https://www.ncbi.nlm.nih.gov/pubmed/32722183 http://dx.doi.org/10.3390/ijms21155261 |
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