Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies

The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could pre...

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Autores principales: Di Costanzo, Margherita, Carucci, Laura, Berni Canani, Roberto, Biasucci, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432728/
https://www.ncbi.nlm.nih.gov/pubmed/32722378
http://dx.doi.org/10.3390/ijms21155275
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author Di Costanzo, Margherita
Carucci, Laura
Berni Canani, Roberto
Biasucci, Giacomo
author_facet Di Costanzo, Margherita
Carucci, Laura
Berni Canani, Roberto
Biasucci, Giacomo
author_sort Di Costanzo, Margherita
collection PubMed
description The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could precede FA, and that particular microbial community structures early in life could influence also the disease course. The identification of gut microbiome features in pediatric FA patients is driving new prevention and treatment approaches. This review is focused on the potential role of the gut microbiome as a target for FA prevention and treatment.
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spelling pubmed-74327282020-08-27 Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies Di Costanzo, Margherita Carucci, Laura Berni Canani, Roberto Biasucci, Giacomo Int J Mol Sci Review The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could precede FA, and that particular microbial community structures early in life could influence also the disease course. The identification of gut microbiome features in pediatric FA patients is driving new prevention and treatment approaches. This review is focused on the potential role of the gut microbiome as a target for FA prevention and treatment. MDPI 2020-07-25 /pmc/articles/PMC7432728/ /pubmed/32722378 http://dx.doi.org/10.3390/ijms21155275 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Di Costanzo, Margherita
Carucci, Laura
Berni Canani, Roberto
Biasucci, Giacomo
Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
title Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
title_full Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
title_fullStr Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
title_full_unstemmed Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
title_short Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
title_sort gut microbiome modulation for preventing and treating pediatric food allergies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432728/
https://www.ncbi.nlm.nih.gov/pubmed/32722378
http://dx.doi.org/10.3390/ijms21155275
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