Cargando…

Molecular Targets, Pathways, and Therapeutic Implications for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) represents one of the leading causes of cancer mortality worldwide. While significant advances have been made for the treatment of advanced hepatocellular carcinoma in the past few years, the prognosis remains poor and effective biomarkers to guide selection of therapi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Jun, Chuang, Jeremy, Cho, May, Toomey, Kyra, Hendifar, Andrew, Li, Daneng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432744/ https://www.ncbi.nlm.nih.gov/pubmed/32718047 http://dx.doi.org/10.3390/ijms21155232

Ejemplares similares

Immunotherapy Updates in Advanced Hepatocellular Carcinoma
por: Singh, Amisha, et al.
Publicado: (2021)

Combination systemic therapies with immune checkpoint inhibitors in pancreatic cancer: overcoming resistance to single-agent checkpoint blockade
por: Gong, Jun, et al.
Publicado: (2018)

Targeting the Fibroblast Growth Factor Receptor (FGFR) in Advanced Cholangiocarcinoma: Clinical Trial Progress and Future Considerations
por: Lee, Patrick C., et al.
Publicado: (2021)

Current Treatment Landscape for Advanced Hepatocellular Carcinoma: Patient Outcomes and the Impact on Quality of Life
por: Li, Daneng, et al.
Publicado: (2019)

Molecular Signaling Pathways and Therapeutic Targets in Hepatocellular Carcinoma
por: Dimri, Manali, et al.
Publicado: (2020)

Therapeutic Advances and Challenges in the Management of HER2-Positive Gastroesophageal Cancers
por: Chuang, Jeremy, et al.
Publicado: (2022)

Adjuvant and Neoadjuvant Treatments for Resectable Hepatocellular Carcinoma
por: Crook, Christiana J., et al.
Publicado: (2023)

Recent Advances in Targeted Therapies for Advanced Gastrointestinal Malignancies
por: C. Huynh, Jasmine, et al.
Publicado: (2020)

Genetic determinants and potential therapeutic targets for pancreatic adenocarcinoma
por: Reznik, Robert, et al.
Publicado: (2014)

Implication of the Hedgehog pathway in hepatocellular carcinoma
por: Della Corte, Carminia Maria, et al.
Publicado: (2017)

Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives
por: Giovannini, Catia, et al.
Publicado: (2016)

Molecular Characterization of Gastric Carcinoma: Therapeutic Implications for Biomarkers and Targets
por: Kankeu Fonkoua, Lionel, et al.
Publicado: (2018)

Advances in prognostic and therapeutic targets for hepatocellular carcinoma and intrahepatic cholangiocarcinoma: The hippo signaling pathway
por: Mranda, Geofrey Mahiki, et al.
Publicado: (2022)

The Molecular Pathogenesis and Clinical Implications of Hepatocellular Carcinoma
por: Meguro, Makoto, et al.
Publicado: (2011)

Bioinformatics analysis of molecular genetic targets and key pathways for hepatocellular carcinoma
por: Tu, Junxue, et al.
Publicado: (2019)

Molecular Targets and Signaling Pathways of microRNA-122 in Hepatocellular Carcinoma
por: Chun, Kwang-Hoon
Publicado: (2022)

Hepatocellular carcinoma subtypes based on metabolic pathways reveals potential therapeutic targets
por: He, Zehua, et al.
Publicado: (2023)

Aldoxorubicin: a tumor-targeted doxorubicin conjugate for relapsed or refractory soft tissue sarcomas
por: Gong, Jun, et al.
Publicado: (2018)

Exploring the JAK/STAT Signaling Pathway in Hepatocellular Carcinoma: Unraveling Signaling Complexity and Therapeutic Implications
por: Park, Hyunjung, et al.
Publicado: (2023)

Hepatocellular Carcinoma: Molecular Pathogenesis and Therapeutic Advances
por: Cucarull, Blanca, et al.
Publicado: (2022)

Novel molecular targets in hepatocellular carcinoma
por: Chow, Ariel Ka-Man, et al.
Publicado: (2020)

Molecular Targets of Ferroptosis in Hepatocellular Carcinoma
por: Liao, Hao, et al.
Publicado: (2021)

Novel Molecular Targets for Hepatocellular Carcinoma
por: Cavalluzzo, Beatrice, et al.
Publicado: (2021)

Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer’s disease
por: Dhapola, Rishika, et al.
Publicado: (2021)

Screening therapeutic targets of ribavirin in hepatocellular carcinoma
por: Xu, Chen, et al.
Publicado: (2018)

Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis
por: Zhou, Lei, et al.
Publicado: (2018)

Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response
por: Lee, Y-H, et al.
Publicado: (2011)

Patient Preferences for Unresectable Hepatocellular Carcinoma Treatments: A Discrete-Choice Experiment
por: Li, Daneng, et al.
Publicado: (2023)

Molecular Pathways in Prolactinomas: Translational and Therapeutic Implications
por: Biagetti, Betina, et al.
Publicado: (2021)

Plasmalemmal Vesicle Associated Protein (PLVAP) as a therapeutic target for treatment of hepatocellular carcinoma
por: Wang, Yun-Hsin, et al.
Publicado: (2014)

Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances
por: Dhanasekaran, Renumathy, et al.
Publicado: (2016)

Nosip is a potential therapeutic target in hepatocellular carcinoma cells
por: Gao, Junjie, et al.
Publicado: (2023)

Key therapeutic targets implicated at the early stage of hepatocellular carcinoma identified through machine-learning approaches
por: Hosseiniyan Khatibi, Seyed Mahdi, et al.
Publicado: (2023)

Risk Factors for Patients with Stage IVB Hepatocellular Carcinoma and Extension into the Heart: Prognostic and Therapeutic Implications
por: Jun, Chung Hwan, et al.
Publicado: (2014)

Investigations of nitazoxanide molecular targets and pathways for the treatment of hepatocellular carcinoma using network pharmacology and molecular docking
por: Khan, Shakeel Ahmad, et al.
Publicado: (2022)

The GH-IGF-SST system in hepatocellular carcinoma: biological and molecular pathogenetic mechanisms and therapeutic targets
por: Pivonello, Claudia, et al.
Publicado: (2014)

Hepatocellular Carcinoma: Molecular Mechanisms and Targeted Therapies
por: Alqahtani, Ali, et al.
Publicado: (2019)

Therapeutic targeting of noncoding RNAs in hepatocellular carcinoma: Recent progress and future prospects
por: Xiao, Zhangang, et al.
Publicado: (2018)

Targeting FGF19/FGFR4 Pathway: A Novel Therapeutic Strategy for Hepatocellular Carcinoma
por: Repana, Dimitra, et al.
Publicado: (2015)

CXCL5/NF-κB Pathway as a Therapeutic Target in Hepatocellular Carcinoma Treatment
por: Jia, Xingqing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i7ac4o7drife9mnjek6ujqn5s2