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Based on the Virtual Screening of Multiple Pharmacophores, Docking and Molecular Dynamics Simulation Approaches toward the Discovery of Novel HPPD Inhibitors

4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an iron-dependent non-heme oxygenase involved in the catabolic pathway of tyrosine, which is an important enzyme in the transformation of 4-hydroxyphenylpyruvic acid to homogentisic acid, and thus being considered as herbicide target. Within this study,...

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Detalles Bibliográficos
Autores principales:	Fu, Ying, Ye, Tong, Liu, Yong-Xuan, Wang, Jian, Ye, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432800/ https://www.ncbi.nlm.nih.gov/pubmed/32756361 http://dx.doi.org/10.3390/ijms21155546

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