Cargando…
Antimicrobial Activity of Small Synthetic Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency
Turgencin A, a potent antimicrobial peptide isolated from the Arctic sea squirt Synoicum turgens, consists of 36 amino acid residues and three disulfide bridges, making it challenging to synthesize. The aim of the present study was to develop a truncated peptide with an antimicrobial drug lead poten...
Autores principales: | Hansen, Ida K. Ø., Lövdahl, Tomas, Simonovic, Danijela, Hansen, Kine Ø., Andersen, Aaron J. C., Devold, Hege, Richard, Céline S. M., Andersen, Jeanette H., Strøm, Morten B., Haug, Tor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432809/ https://www.ncbi.nlm.nih.gov/pubmed/32751755 http://dx.doi.org/10.3390/ijms21155460 |
Ejemplares similares
-
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
por: Dey, Hymonti, et al.
Publicado: (2022) -
Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens
por: Hansen, Ida K. Ø., et al.
Publicado: (2020) -
The Expression of Antibacterial Peptide Turgencin A in Pichia pastoris and an Analysis of Its Antibacterial Activity
por: Dong, Chunming, et al.
Publicado: (2023) -
C-Locked Analogs of the Antimicrobial Peptide BP214
por: Andersen, Ida Kristine Lysgaard, et al.
Publicado: (2022) -
Small molecules enhance the potency of natural antimicrobial peptides
por: Losasso, Valeria, et al.
Publicado: (2022)