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Increased Oxidative Phosphorylation Is Required for Stemness Maintenance in Liver Cancer Stem Cells from Hepatocellular Carcinoma Cell Line HCCLM3 Cells

Cancer stem cells (CSCs) are considered to be the main cause of tumor recurrence, metastasis, and an unfavorable prognosis. Energy metabolism is closely associated with cell stemness. However, how the stemness of liver cancer stem cells (LCSCs) is regulated by metabolic/oxidative stress remains poor...

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Detalles Bibliográficos
Autores principales: Liu, Ge, Luo, Qing, Li, Hong, Liu, Qiuping, Ju, Yang, Song, Guanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432880/
https://www.ncbi.nlm.nih.gov/pubmed/32722385
http://dx.doi.org/10.3390/ijms21155276