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Exploring IDP–Ligand Interactions: Tau K18 as a Test Case

Over the past decade intrinsically disordered proteins (IDPs) have emerged as a biologically important class of proteins, many of which are of therapeutic relevance. Here, we investigated the interactions between a model IDP system, tau K18, and nine literature compounds that have been reported as h...

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Detalles Bibliográficos
Autores principales: Vagrys, Darius, Davidson, James, Chen, Ijen, Hubbard, Roderick E., Davis, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432903/
https://www.ncbi.nlm.nih.gov/pubmed/32722166
http://dx.doi.org/10.3390/ijms21155257