Bacteroides fragilis Enterotoxin Induces Sulfiredoxin-1 Expression in Intestinal Epithelial Cell Lines Through a Mitogen-Activated Protein Kinases- and Nrf2-Dependent Pathway, Leading to the Suppression of Apoptosis

Enterotoxigenic Bacteroides fragilis is a causative agent of colitis and secrets enterotoxin (BFT), leading to the disease. Sulfiredoxin (Srx)-1 serves to protect from oxidative damages. Although BFT can generate reactive oxygen species in intestinal epithelial cells (IECs), no Srx-1 expression has...

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Detalles Bibliográficos
Autores principales: Jeon, Jong Ik, Choi, Jun Ho, Lee, Keun Hwa, Kim, Jung Mogg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432937/
https://www.ncbi.nlm.nih.gov/pubmed/32751114
http://dx.doi.org/10.3390/ijms21155383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432937/
https://www.ncbi.nlm.nih.gov/pubmed/32751114
http://dx.doi.org/10.3390/ijms21155383

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