An international randomized phase III trial of pulse actinomycin-D versus multi-day methotrexate for the treatment of low risk gestational trophoblastic neoplasia; NRG/GOG 275

OBJECTIVES. Methotrexate and actinomycin-D are both effective first-line drugs for low-risk (WHO score 0–6) Gestational Trophoblastic Neoplasia (GTN) with considerable debate about which is more effective, less toxic, and better tolerated. The primary trial objective was to test if treatment with mu...

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Detalles Bibliográficos
Autores principales: Schink, Julian C., Filiaci, Virginia, Huang, Helen Q., Tidy, John, Winter, Matthew, Carter, Jeanne, Anderson, Nancy, Moxley, Katherine, Yabuno, Akira, Taylor, Sarah E., Kushnir, Christina, Horowitz, Neil, Miller, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432963/
https://www.ncbi.nlm.nih.gov/pubmed/32460997
http://dx.doi.org/10.1016/j.ygyno.2020.05.013

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