Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit dysfunction in adults with Down syndrome

BACKGROUND: Alzheimer’s disease (AD) is the major cause of death in adults with Down syndrome (DS). There is an urgent need for objective markers of AD in the DS population to improve early diagnosis and monitor disease progression. NPTX2 has recently emerged as a promising cerebrospinal fluid (CSF)...

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Detalles Bibliográficos
Autores principales: Belbin, Olivia, Xiao, Mei-Fang, Xu, Desheng, Carmona-Iragui, Maria, Pegueroles, Jordi, Benejam, Bessy, Videla, Laura, Fernández, Susana, Barroeta, Isabel, Nuñez-Llaves, Raúl, Montal, Victor, Vilaplana, Eduard, Altuna, Miren, Clarimón, Jordi, Alcolea, Daniel, Blesa, Rafael, Lleó, Alberto, Worley, Paul F., Fortea, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433053/
https://www.ncbi.nlm.nih.gov/pubmed/32807227
http://dx.doi.org/10.1186/s13024-020-00398-0

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