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Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma

BACKGROUND: SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitrosamine (DEN)-induced HCC. As SOCS1 and SOCS3 are important...

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Detalles Bibliográficos
Autores principales:	Khan, Md Gulam Musawwir, Ghosh, Amit, Variya, Bhavesh, Santharam, Madanraj Appiya, Ihsan, Awais Ullah, Ramanathan, Sheela, Ilangumaran, Subburaj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433106/ https://www.ncbi.nlm.nih.gov/pubmed/32807134 http://dx.doi.org/10.1186/s12885-020-07285-3

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