CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis

BACKGROUND: Extracellular vesicles (EVs) released by neurons and glia reach the cerebrospinal fluid (CSF). Studying the proteome of CSF-derived EVs offers a novel perspective on the key intracellular processes associated with the pathogenesis of the neurodegenerative disease amyotrophic lateral scle...

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Detalles Bibliográficos
Autores principales: Thompson, Alexander G., Gray, Elizabeth, Mäger, Imre, Thézénas, Marie-Laëtitia, Charles, Philip D., Talbot, Kevin, Fischer, Roman, Kessler, Benedikt M., Wood, Mathew, Turner, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433176/
https://www.ncbi.nlm.nih.gov/pubmed/32821252
http://dx.doi.org/10.1186/s12014-020-09294-7

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