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The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy
Cancer is characterized as a complex disease caused by coordinated alterations of multiple signaling pathways. The Ras/RAF/MEK/ERK (MAPK) signaling is one of the best-defined pathways in cancer biology, and its hyperactivation is responsible for over 40% human cancer cases. To drive carcinogenesis,...
Autores principales: | Yuan, Jimin, Dong, Xiaoduo, Yap, Jiajun, Hu, Jiancheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433213/ https://www.ncbi.nlm.nih.gov/pubmed/32807225 http://dx.doi.org/10.1186/s13045-020-00949-4 |
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