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Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen

CLINICAL/METHODOLOGICAL ISSUE: COVID-19 is a new viral disease that is associated with inflammatory pulmonary changes which can be detected in computed tomography (CT). So far postmortem CT (PMCT) has not been used as a screening instrument for the evaluation of deaths with and without autopsy. In t...

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Autores principales: Kniep, I., Lutter, M., Ron, A., Edler, C., Püschel, K., Ittrich, H., Heller, M., Heinemann, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433282/
https://www.ncbi.nlm.nih.gov/pubmed/32809036
http://dx.doi.org/10.1007/s00117-020-00733-y
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author Kniep, I.
Lutter, M.
Ron, A.
Edler, C.
Püschel, K.
Ittrich, H.
Heller, M.
Heinemann, A.
author_facet Kniep, I.
Lutter, M.
Ron, A.
Edler, C.
Püschel, K.
Ittrich, H.
Heller, M.
Heinemann, A.
author_sort Kniep, I.
collection PubMed
description CLINICAL/METHODOLOGICAL ISSUE: COVID-19 is a new viral disease that is associated with inflammatory pulmonary changes which can be detected in computed tomography (CT). So far postmortem CT (PMCT) has not been used as a screening instrument for the evaluation of deaths with and without autopsy. In this respect, its validity has to be proved in comparison to clinical–radiological experiences. STANDARD RADIOLOGICAL METHODS: Postmortem CT METHODICAL INNOVATIONS: So far, PMCT can be regarded as a methodological innovation that has not yet been sufficiently evaluated for pneumonia. PERFORMANCE: CT in clinical routine has a high sensitivity for pneumonia. However, to what extent postmortem artifacts are relevant to PMCT still has to be determined. ACHIEVEMENTS: There is still no standard procedure for the postmortem radiological diagnosis of COVID-19 disease. Despite postmortem artifacts, PMCT can provide valuable information about the presence of pneumonia with interstitial character, especially without autopsy. PRACTICAL RECOMMENDATIONS: PMCT is particularly useful in the assessment of suspected cases of COVID-19 pneumonia for morphological assessment in the context of monitoring deaths in the current pandemic situation.
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spelling pubmed-74332822020-08-18 Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen Kniep, I. Lutter, M. Ron, A. Edler, C. Püschel, K. Ittrich, H. Heller, M. Heinemann, A. Radiologe Leitthema CLINICAL/METHODOLOGICAL ISSUE: COVID-19 is a new viral disease that is associated with inflammatory pulmonary changes which can be detected in computed tomography (CT). So far postmortem CT (PMCT) has not been used as a screening instrument for the evaluation of deaths with and without autopsy. In this respect, its validity has to be proved in comparison to clinical–radiological experiences. STANDARD RADIOLOGICAL METHODS: Postmortem CT METHODICAL INNOVATIONS: So far, PMCT can be regarded as a methodological innovation that has not yet been sufficiently evaluated for pneumonia. PERFORMANCE: CT in clinical routine has a high sensitivity for pneumonia. However, to what extent postmortem artifacts are relevant to PMCT still has to be determined. ACHIEVEMENTS: There is still no standard procedure for the postmortem radiological diagnosis of COVID-19 disease. Despite postmortem artifacts, PMCT can provide valuable information about the presence of pneumonia with interstitial character, especially without autopsy. PRACTICAL RECOMMENDATIONS: PMCT is particularly useful in the assessment of suspected cases of COVID-19 pneumonia for morphological assessment in the context of monitoring deaths in the current pandemic situation. Springer Medizin 2020-08-18 2020 /pmc/articles/PMC7433282/ /pubmed/32809036 http://dx.doi.org/10.1007/s00117-020-00733-y Text en © Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Leitthema
Kniep, I.
Lutter, M.
Ron, A.
Edler, C.
Püschel, K.
Ittrich, H.
Heller, M.
Heinemann, A.
Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen
title Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen
title_full Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen
title_fullStr Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen
title_full_unstemmed Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen
title_short Postmortale Bildgebung der Lunge bei COVID-19-Todesfällen
title_sort postmortale bildgebung der lunge bei covid-19-todesfällen
topic Leitthema
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433282/
https://www.ncbi.nlm.nih.gov/pubmed/32809036
http://dx.doi.org/10.1007/s00117-020-00733-y
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