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Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions
BACKGROUND: African Americans (AA) are at high risk for Colorectal Cancer (CRC). Studies report a 30–60% increase in CRC risk with physical inactivity, obesity and metabolic syndrome. Activation of the WNT/β-catenin (CTNNB1) signaling pathway plays a critical role in colorectal carcinogenesis. Accum...
Autores principales: | Shokrani, Babak, Brim, Hassan, Hydari, Tahmineh, Afsari, Ali, Lee, Edward, Nouraie, Mehdi, Sherif, Zaki, Ashktorab, Hassan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433356/ https://www.ncbi.nlm.nih.gov/pubmed/32811441 http://dx.doi.org/10.1186/s12876-020-01412-x |
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