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Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis
Adipocytes deficient in fatty acid synthase (iAdFASNKO) emit signals that mimic cold exposure to enhance the appearance of thermogenic beige adipocytes in mouse inguinal white adipose tissues (iWATs). Both cold exposure and iAdFASNKO upregulate the sympathetic nerve fiber (SNF) modulator Neuregulin...
Autores principales: | Henriques, Felipe, Bedard, Alexander H., Guilherme, Adilson, Kelly, Mark, Chi, Jingyi, Zhang, Peng, Lifshitz, Lawrence M., Bellvé, Karl, Rowland, Leslie A., Yenilmez, Batuhan, Kumar, Shreya, Wang, Yetao, Luban, Jeremy, Weinstein, Lee S., Lin, Jiandie D., Cohen, Paul, Czech, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433376/ https://www.ncbi.nlm.nih.gov/pubmed/32755590 http://dx.doi.org/10.1016/j.celrep.2020.107998 |
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