Cargando…

Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NF-κB Signaling Pathway

Cerebral ischemia is a major cause of brain dysfunction, neuroinflammation and oxidative stress have been implicated in the pathophysiological process of cerebral ischemia/reperfusion injury. Celastrol is a potent inhibitor of inflammation and oxidative stress that has little toxicity. The present s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Bo, Zhong, Qi, Chen, Xuhui, Wu, Xi, Sha, Rong, Song, Guizhi, Zhang, Chuanhan, Chen, Xiangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433406/ https://www.ncbi.nlm.nih.gov/pubmed/32848589 http://dx.doi.org/10.3389/fnins.2020.00847

Ejemplares similares

Corrigendum: Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NF-κB Signaling Pathway
por: Zhang, Bo, et al.
Publicado: (2021)

Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion
por: Liu, Dan-Dan, et al.
Publicado: (2021)

Neuroprotection of antioxidant enzymes against transient global cerebral ischemia in gerbils
por: Lee, Jae-Chul, et al.
Publicado: (2014)

Engeletin alleviates cerebral ischemia reperfusion‐induced neuroinflammation via the HMGB1/TLR4/NF‐κB network
por: Xu, Yangyang, et al.
Publicado: (2023)

Neuroprotective effect of paricalcitol in a rat model of transient global cerebral ischemia
por: Kim, Sung Wook, et al.
Publicado: (2020)

Celastrol induces apoptosis of gastric cancer cells by miR-146a inhibition of NF-κB activity
por: Sha, Min, et al.
Publicado: (2013)

Neuroprotection of Dexmedetomidine against Cerebral Ischemia-Reperfusion Injury in Rats: Involved in Inhibition of NF-κB and Inflammation Response
por: Wang, Lijun, et al.
Publicado: (2017)

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function
por: Yu, Xiaowen, et al.
Publicado: (2018)

Neuroprotection by triptolide against cerebral ischemia/reperfusion injury through the inhibition of NF-κB/PUMA signal in rats
por: Zhang, Bin, et al.
Publicado: (2016)

Neuroprotective effects of Ilexonin A following transient focal cerebral ischemia in rats
por: XU, AI-LING, et al.
Publicado: (2016)

Neuroprotective Effect of Xueshuantong for Injection (Lyophilized) in Transient and Permanent Rat Cerebral Ischemia Model
por: Wang, Xumei, et al.
Publicado: (2015)

Effect of Celastrol on LncRNAs and mRNAs Profiles of Cerebral Ischemia-Reperfusion Injury in Transient Middle Cerebral Artery Occlusion Mice Model
por: Liu, Jiandong, et al.
Publicado: (2022)

Neuroprotective Effects of Musk of Muskrat on Transient Focal Cerebral Ischemia in Rats
por: Lee, Donghun, et al.
Publicado: (2019)

Neuroprotective Activity of Lavender Oil on Transient Focal Cerebral Ischemia in Mice
por: Wang, Dong, et al.
Publicado: (2012)

Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia
por: Amantea, Diana, et al.
Publicado: (2019)

HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways
por: Xie, Weijie, et al.
Publicado: (2019)

TLR5 Activation through NF-κB Is a Neuroprotective Mechanism of Postconditioning after Cerebral Ischemia in Mice
por: Jeong, Jaewon, et al.
Publicado: (2017)

Neuroprotective effect of menaquinone-4 (MK-4) on transient global cerebral ischemia/reperfusion injury in rat
por: Farhadi Moghadam, Bahram, et al.
Publicado: (2020)

Neuroprotection by salubrinal treatment in global cerebral ischemia
por: Anuncibay-Soto, Berta, et al.
Publicado: (2016)

The Role of NF-κB Triggered Inflammation in Cerebral Ischemia
por: Jover-Mengual, Teresa, et al.
Publicado: (2021)

Celastrol ameliorates osteoarthritis via regulating TLR2/NF-κB signaling pathway
por: Yang, Guangxia, et al.
Publicado: (2022)

Neuroprotective Effect of Kaempferol Glycosides against Brain Injury and Neuroinflammation by Inhibiting the Activation of NF-κB and STAT3 in Transient Focal Stroke
por: Yu, Lu, et al.
Publicado: (2013)

Salvianolic Acid D Alleviates Cerebral Ischemia-Reperfusion Injury by Suppressing the Cytoplasmic Translocation and Release of HMGB1-Triggered NF-κB Activation to Inhibit Inflammatory Response
por: Zhang, Wen, et al.
Publicado: (2020)

Celastrol Blocks Interleukin-6 Gene Expression via Downregulation of NF-κB in Prostate Carcinoma Cells
por: Chiang, Kun-Chun, et al.
Publicado: (2014)

Neuroprotective Effects of Quetiapine on Neuronal Apoptosis Following Experimental Transient Focal Cerebral Ischemia in Rats
por: Yılmaz, Muhammet Bahadır, et al.
Publicado: (2013)

Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation
por: Sapkota, Arjun, et al.
Publicado: (2017)

Neuroprotective Effects of Tryptanthrin-6-Oxime in a Rat Model of Transient Focal Cerebral Ischemia
por: Plotnikov, Mark B., et al.
Publicado: (2023)

Resveratrol affects the migration and apoptosis of monocytes by blocking HMGB1/NF-κB pathway
por: Zhang, Yuwei, et al.
Publicado: (2021)

Amentoflavone attenuates oxidative stress and neuroinflammation induced by cerebral ischemia/reperfusion in rats by targeting HMGB1-mediated TLR4/NF-κB signaling pathway
por: Saeedan, Abdulaziz S., et al.
Publicado: (2023)

Protective effect of celastrol on myocardial ischemia–reperfusion injury
por: Li, Xiaoyan, et al.
Publicado: (2017)

Neuroprotective Effects of Ginsenosides against Cerebral Ischemia
por: Cheng, Zhekang, et al.
Publicado: (2019)

Monocarboxylate transporter 4 plays a significant role in the neuroprotective mechanism of ischemic preconditioning in transient cerebral ischemia
por: Hong, Seongkweon, et al.
Publicado: (2015)

Effect of Tetramethylpyrazine on Neuroplasticity after Transient Focal Cerebral Ischemia Reperfusion in Rats
por: Lin, Junbin, et al.
Publicado: (2021)

bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
por: Sun, Dawei, et al.
Publicado: (2018)

Inhibiting HMGB1 Reduces Cerebral Ischemia Reperfusion Injury in Diabetic Mice
por: Wang, Chong, et al.
Publicado: (2016)

microRNA-130a-5p suppresses myocardial ischemia reperfusion injury by downregulating the HMGB2/NF-κB axis
por: Li, Yong, et al.
Publicado: (2021)

Neuroprotective Effects of Celastrol in Neurodegenerative Diseases-Unscramble Its Major Mechanisms of Action and Targets
por: Liu, Dandan, et al.
Publicado: (2022)

Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice
por: Kim, Jung Eun, et al.
Publicado: (2013)

Lipidomic Profiling of Ipsilateral Brain and Plasma after Celastrol Post-Treatment in Transient Middle Cerebral Artery Occlusion Mice Model
por: Liu, Maozhu, et al.
Publicado: (2021)

Neuroprotective effects of rutaecarpine on cerebral ischemia reperfusion injury
por: Yan, Chunlin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b1hc5852dndetb26v6ulr05beh