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Neural compensation in presymptomatic hAPP mouse models of Alzheimer's disease
Largely inspired from clinical concepts like brain reserve, cognitive reserve, and neural compensation, here we review data showing how neural circuits reorganize in presymptomatic and early symptomatic hAPP mice to maintain memory intact. By informing on molecular alterations and compensatory adapt...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433654/ https://www.ncbi.nlm.nih.gov/pubmed/32817305 http://dx.doi.org/10.1101/lm.050401.119 |