C1222C Deletion in Exon 8 of ABL1 Is Involved in Carcinogenesis and Cell Cycle Control of Colorectal Cancer Through IRS1/PI3K/Akt Pathway

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. ABL1 (c-Abl) is a non-receptor tyrosine kinase, whose role, and molecular mechanism in CRC remain largely unclear. The aim of this study was to elucidate the role of ABL1 to obtain information on colon cancer gene mutat...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Cao, Jian, Zhu, Ya-Ning, Ma, Yu, Murtaza, Ghulam, Li, Yu, Wang, Jian-Hua, Pu, Yan-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433659/
https://www.ncbi.nlm.nih.gov/pubmed/32850446
http://dx.doi.org/10.3389/fonc.2020.01385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433659/
https://www.ncbi.nlm.nih.gov/pubmed/32850446
http://dx.doi.org/10.3389/fonc.2020.01385

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