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The structure-based reaction mechanism of urease, a nickel dependent enzyme: tale of a long debate

This review is an attempt to retrace the chronicle that starts from the discovery of the role of nickel as the essential metal ion in urease for the enzymatic catalysis of urea, a key step in the biogeochemical cycle of nitrogen on Earth, to the most recent progress in understanding the chemistry of...

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Detalles Bibliográficos
Autores principales: Mazzei, Luca, Musiani, Francesco, Ciurli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433671/
https://www.ncbi.nlm.nih.gov/pubmed/32809087
http://dx.doi.org/10.1007/s00775-020-01808-w