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Spatial Distribution Profiles of Emtricitabine, Tenofovir, Efavirenz, and Rilpivirine in Murine Tissues Following In Vivo Dosing Correlate with Their Safety Profiles in Humans

[Image: see text] Emtricitabine (FTC), tenofovir (TFV), efavirenz (EFV), and rilpivirine (RPV) are currently used as components of HIV combination therapy. Although these drugs are widely used in antiretroviral therapy, several organ toxicities related to TFV and EFV have been observed clinically. T...

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Detalles Bibliográficos
Autores principales:	Seneviratne, Herana Kamal, Hamlin, Allyson N., Heck, Carley J. S., Bumpus, Namandjé N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433710/ https://www.ncbi.nlm.nih.gov/pubmed/32832868 http://dx.doi.org/10.1021/acsptsci.0c00015

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