Circ‐SPECC1 modulates TGFβ2 and autophagy under oxidative stress by sponging miR‐33a to promote hepatocellular carcinoma tumorigenesis

Circular RNAs (circRNAs) play vital roles in the pathogenesis and development of multiple cancers, including hepatocellular carcinoma (HCC). Nevertheless, the regulatory mechanisms of circ‐SPECC1 in HCC remain poorly understood. In our study, we found that circ‐SPECC1 was apparently downregulated in...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Liu, Zhiyi, Cao, Kuan, Shan, Wengang, Liu, Jin, Wen, Quan, Wang, Renhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433841/
https://www.ncbi.nlm.nih.gov/pubmed/32627938
http://dx.doi.org/10.1002/cam4.3219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433841/
https://www.ncbi.nlm.nih.gov/pubmed/32627938
http://dx.doi.org/10.1002/cam4.3219

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