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Could imiquimod (Aldara 5% cream) or other TLR7 agonists be used in the treatment of COVID-19?
Toll-like receptor 7 is critical in recognition of single strand RNA viruses, including SARS CoV-2, and generation of anti-viral immunity. Coronaviruses evolved strategies to dampen the host immunity. Herein, we discuss the potential use of TLR7 agonists in the early stages of COVID-19 treatment.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434307/ https://www.ncbi.nlm.nih.gov/pubmed/33254510 http://dx.doi.org/10.1016/j.mehy.2020.110202 |