When to rule out COVID-19: How many negative RT-PCR tests are needed?

Amidst the COVID-19 pandemic, clinicians have been plagued with dilemmas related to the uncertainty about diagnostic testing for the virus. It has become commonplace for a patient under investigation (PUI) to repeatedly test negative but have imaging findings that are consistent with COVID-19. This...

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Detalles Bibliográficos
Autores principales: Isikbay, Masis, Henry, Travis S., Frank, James A., Hope, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434325/
https://www.ncbi.nlm.nih.gov/pubmed/32837902
http://dx.doi.org/10.1016/j.rmcr.2020.101192
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author Isikbay, Masis
Henry, Travis S.
Frank, James A.
Hope, Michael D.
author_facet Isikbay, Masis
Henry, Travis S.
Frank, James A.
Hope, Michael D.
author_sort Isikbay, Masis
collection PubMed
description Amidst the COVID-19 pandemic, clinicians have been plagued with dilemmas related to the uncertainty about diagnostic testing for the virus. It has become commonplace for a patient under investigation (PUI) to repeatedly test negative but have imaging findings that are consistent with COVID-19. This raises the question of when the treating team should entertain alternative diagnoses. We present such a case to help provide a framework for how to weigh repeatedly negative test results in clinical decision making when there is ongoing concern for COVID-19.
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spelling pubmed-74343252020-08-19 When to rule out COVID-19: How many negative RT-PCR tests are needed? Isikbay, Masis Henry, Travis S. Frank, James A. Hope, Michael D. Respir Med Case Rep Case Report Amidst the COVID-19 pandemic, clinicians have been plagued with dilemmas related to the uncertainty about diagnostic testing for the virus. It has become commonplace for a patient under investigation (PUI) to repeatedly test negative but have imaging findings that are consistent with COVID-19. This raises the question of when the treating team should entertain alternative diagnoses. We present such a case to help provide a framework for how to weigh repeatedly negative test results in clinical decision making when there is ongoing concern for COVID-19. Elsevier 2020-08-18 /pmc/articles/PMC7434325/ /pubmed/32837902 http://dx.doi.org/10.1016/j.rmcr.2020.101192 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Isikbay, Masis
Henry, Travis S.
Frank, James A.
Hope, Michael D.
When to rule out COVID-19: How many negative RT-PCR tests are needed?
title When to rule out COVID-19: How many negative RT-PCR tests are needed?
title_full When to rule out COVID-19: How many negative RT-PCR tests are needed?
title_fullStr When to rule out COVID-19: How many negative RT-PCR tests are needed?
title_full_unstemmed When to rule out COVID-19: How many negative RT-PCR tests are needed?
title_short When to rule out COVID-19: How many negative RT-PCR tests are needed?
title_sort when to rule out covid-19: how many negative rt-pcr tests are needed?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434325/
https://www.ncbi.nlm.nih.gov/pubmed/32837902
http://dx.doi.org/10.1016/j.rmcr.2020.101192
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