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Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen
INTRODUCTION: Observational studies estimating severe outcomes for paracetamol versus ibuprofen use have acknowledged the specific challenge of channeling bias. A previous study relying on negative controls suggested that using large-scale propensity score (LSPS) matching may mitigate bias better th...
Autores principales: | Weinstein, Rachel B., Ryan, Patrick B., Berlin, Jesse A., Schuemie, Martijn J., Swerdel, Joel, Fife, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434801/ https://www.ncbi.nlm.nih.gov/pubmed/32500272 http://dx.doi.org/10.1007/s40264-020-00950-3 |
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