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Modulation of P2Y(6)R expression exacerbates pressure overload-induced cardiac remodeling in mice

Cardiac tissue remodeling caused by hemodynamic overload is a major clinical outcome of heart failure. Uridine-responsive purinergic P2Y(6) receptor (P2Y(6)R) contributes to the progression of cardiovascular remodeling in rodents, but it is not known whether inhibition of P2Y(6)R prevents or promote...

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Detalles Bibliográficos
Autores principales:	Shimoda, Kakeru, Nishimura, Akiyuki, Sunggip, Caroline, Ito, Tomoya, Nishiyama, Kazuhiro, Kato, Yuri, Tanaka, Tomohiro, Tozaki-Saitoh, Hidetoshi, Tsuda, Makoto, Nishida, Motohiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434875/ https://www.ncbi.nlm.nih.gov/pubmed/32811872 http://dx.doi.org/10.1038/s41598-020-70956-5

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