DNA Encapsidation and Capsid Assembly Are Underexploited Antiviral Targets for the Treatment of Herpesviruses

Although there are effective nucleoside analogs to treat HSV, VZV, and HCMV disease, herpesvirus infections continue to contribute to significant morbidity and mortality. Acyclovir is the drug of choice for HSV encephalopathy, yet there is an estimated 6–19% mortality rate with half of the survivors...

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Detalles Bibliográficos
Autores principales: Keil, Tara, Liu, Dongmei, Lloyd, Megan, Coombs, Wanda, Moffat, Jennifer, Visalli, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434925/
https://www.ncbi.nlm.nih.gov/pubmed/32903425
http://dx.doi.org/10.3389/fmicb.2020.01862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434925/
https://www.ncbi.nlm.nih.gov/pubmed/32903425
http://dx.doi.org/10.3389/fmicb.2020.01862

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