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DNA Encapsidation and Capsid Assembly Are Underexploited Antiviral Targets for the Treatment of Herpesviruses
Although there are effective nucleoside analogs to treat HSV, VZV, and HCMV disease, herpesvirus infections continue to contribute to significant morbidity and mortality. Acyclovir is the drug of choice for HSV encephalopathy, yet there is an estimated 6–19% mortality rate with half of the survivors...
Autores principales: | Keil, Tara, Liu, Dongmei, Lloyd, Megan, Coombs, Wanda, Moffat, Jennifer, Visalli, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434925/ https://www.ncbi.nlm.nih.gov/pubmed/32903425 http://dx.doi.org/10.3389/fmicb.2020.01862 |
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