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Linking Alpha-Synuclein to the Actin Cytoskeleton: Consequences to Neuronal Function

Alpha-Synuclein (αSyn), a protein highly enriched in neurons where it preferentially localizes at the pre-synapse, has been in the spotlight because its intraneuronal aggregation is a central phenomenon in Parkinson’s disease. However, the consequences of αSyn accumulation to neuronal function are n...

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Detalles Bibliográficos
Autores principales: Oliveira da Silva, Marina I., Liz, Márcia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434970/
https://www.ncbi.nlm.nih.gov/pubmed/32903460
http://dx.doi.org/10.3389/fcell.2020.00787