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Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT

Infections with the pathogenic bacterium Clostridioides (C.) difficile are coming more into focus, in particular in hospitalized patients after antibiotic treatment. C. difficile produces the exotoxins TcdA and TcdB. Since some years, hypervirulent strains are described, which produce in addition th...

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Detalles Bibliográficos
Autores principales:	Korbmacher, Michael, Fischer, Stephan, Landenberger, Marc, Papatheodorou, Panagiotis, Aktories, Klaus, Barth, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435013/ https://www.ncbi.nlm.nih.gov/pubmed/32903430 http://dx.doi.org/10.3389/fphar.2020.01204

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