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Urine Metabolomics Study on Potential Hepatoxic Biomarkers Identification in Rats Induced by Aurantio-Obtusin

Previous studies revealed the hepatotoxic effect of aurantio-obtusin on rats. The aim of this study was to identify potential biomarkers of urine caused by aurantio-obtusin. Sprague–Dawley (SD) rats with body weight of 0, 4, 40, and 200 mg/kg were orally given aurantio-obtusin for 28 days, and urine...

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Detalles Bibliográficos
Autores principales:	Xu, Longlong, Wang, Yuguang, Ma, Zengchun, Tang, Xianglin, Gao, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435054/ https://www.ncbi.nlm.nih.gov/pubmed/32903457 http://dx.doi.org/10.3389/fphar.2020.01237

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