Targeting cPLA(2) derived lipid hydroperoxides as a potential intervention for sarcopenia

Defects in neuromuscular innervation contribute significantly to the age-related decline in muscle mass and function (sarcopenia). Our previous studies demonstrated that denervation induces muscle mitochondrial hydroperoxide production (H(2)O(2) and lipid hydroperoxides (LOOHs)). Here we define the...

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Detalles Bibliográficos
Autores principales: Pharaoh, Gavin, Brown, Jacob L., Sataranatarajan, Kavithalakshmi, Kneis, Parker, Bian, Jan, Ranjit, Rojina, Hadad, Niran, Georgescu, Constantin, Rabinovitch, Peter, Ran, Qitao, Wren, Jonathan D., Freeman, Willard, Kinter, Michael, Richardson, Arlan, Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435184/
https://www.ncbi.nlm.nih.gov/pubmed/32811851
http://dx.doi.org/10.1038/s41598-020-70792-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435184/
https://www.ncbi.nlm.nih.gov/pubmed/32811851
http://dx.doi.org/10.1038/s41598-020-70792-7

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